Ketamine Intervention Program for Treatment-Resistant Depression

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healthcare worker with a patient

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The outpatient Ketamine Intervention Program helps adults who have not benefited from other antidepressants and therapy for Treatment-Resistant Depression (TRD).

What to expect

Ketamine is a medication used as an anesthetic and as a treatment for depression. At low doses, ketamine is highly effective medication for adults who have not benefited from other antidepressants and therapy for TRD.

Generally, ketamine is not used by itself to treat depression; it is used to accelerate the antidepressant effect of the other treatments, which can help change pathways in the brain.

Resources

Eligibility

Adults who have not benefited from other antidepressants and therapy for TRD may be eligible for the Ketamine Intervention Program.

This treatment is not suitable for individuals who are pregnant or breastfeeding or those with:

  • Allergies to ketamine or related compounds
  • Certain psychiatric conditions
  • A history of ketamine use disorder
  • Alcohol or substance use disorder within the past six months
  • Certain antidepressant medications such as monoamine oxidase inhibitors
  • Dementia or delirium
  • Certain heart conditions
  • Uncontrolled hypertension
  • Recent seizures
  • A history of increased intracranial pressure

Find this service near you

OR
  • Ketamine Intervention Program at Squamish General Hospital

    38140 Behrner Drive Squamish
  • Ketamine Intervention Program at UBC Hospital

    Detwiller Pavilion, UBC Hospital 2255 Wesbrook Mall Vancouver